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Is Your Daily Caffeine Fix Affecting Your Kidney Health?

The Everyday Dose Team
5 min read

Could your coffee fix be having a negative impact on kidney health? Your CYP1A2 gene may hold the key.  

( What the Heck is a CYP1A2 Gene? )

Imagine your cells as a busy coffee shop. This gene is the employee tasked with handling the ‘order’ of processing caffeine. However, just like in an overcrowded Starbucks, some baristas handle the rush better than others. Similarly, genetic variations in CYP1A2 impact how fast or slow your body metabolizes caffeine – and it turns out over 60% of the population has this potentially dangerous variant.

The Staggering Statistics

So, back to the real question. Is your daily caffeine fix affecting your kidney health? The answer, quite surprisingly, is a loud and clear 'Yes'. Among folks with a specific variant in the CYP1A2 gene (slow caffeine metabolizers), heavy coffee consumption was linked to a higher likelihood of kidney issues. We're talking numbers like 270% more likely to develop serious issues, such as albuminuria, and 280% more likely to develop hypertension throughout this long-spanning study.[1] Wow, right?

Sip on this...

The takeaway? Not all of us react to coffee the same way, thanks to our genetic makeup. Over half the population is over 200% more likely to develop dangerous kidney diseases and suffer from other risky side effects from consuming too much coffee.

Signs You Might Have this Genotype:

✔️ Can't drink coffee in the afternoon if you want to sleep

✔️ Often anxious or jittery after consuming caffeine

* As always, this isn't medical advice. We always recommend you consult a healthcare professional if you have questions or concerns about your health.


Absolutely NOT -- we created Everyday Dose for people like you (and us!), who still want to enjoy the taste, ritual, and energy you love about coffee, without all the side effects and with LOADS of added benefits.

Coffee Without The Compromise

Our mushroom drinks are everything you love about coffee with a ton of added benefits – and none of the side effects. Trade the afternoon crash, jitters, anxiety, and gut issues for all-day energy, focus, clarity, better sleep, boosted immunity, and a healthier gut.

Making the Switch From Coffee to Mushroom Coffee Can Promote Kidney Health and...

Enhance Focus and Concentration:

Lion's mane supports cognitive function and may help improve
concentration and focus.

Balance Energy Levels:

Everyday Dose provides a smoother and more sustained energy
boost compared to traditional coffee. This can lead to reduced jitters and

Adaptogenic Properties:

Certain mushrooms, like chaga, are considered adaptogens.
They help the body adapt to stress and support overall well-being.

Reduce Coffee Jitters:

The combination of mushrooms and coffee is believed to
mitigate the jittery feeling often associated with regular coffee consumption. 

Antioxidant Boost:

Mushrooms, particularly chaga, are rich in antioxidants that
help combat oxidative stress and protect the body from free radicals.

Supports Immune Function:

Chaga has immune-boosting properties, contributing to a
healthier immune system.

Gut Health Benefits:

Our mushroom coffee promotes the growth of beneficial gut
bacteria and supporting digestive health.

Anti-Inflammatory Effects:

The chaga in Everyday Dose has anti-inflammatory properties
that could help in reducing inflammation in the body.


[1] Mahdavi, Sara et al. “CYP1A2 Genetic Variation, Coffee Intake, and Kidney Dysfunction.” JAMA network open vol. 6,1 e2247868. 3 Jan. 2023, doi:10.1001/jamanetworkopen.2022.47868 https://www.everydaydose.com/pages/CYP1A2-Genetic-Variation-CoffeeIntakeandKidneyDysfunction

The Everyday Dose Team
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